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INTERFERON REGULATORY FACTORS
Descriptors Found:
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DeCS
Descriptor
English
:
Interferon Regulatory Factors
Descriptor
Spanish
:
Factores Reguladores del Interferón
Descriptor
Portuguese
:
Fatores Reguladores de Interferon
Synonyms
English
:
IRF Transcription Factors
Transcription Factors, IRF
Tree Number:
D12.644.360.024.302
D12.776.157.057.050
D12.776.260.504
D12.776.476.024.385
D12.776.930.332
Definition
English
:
A
family
of
transcription factors
that share an N-terminal HELIX-TURN-HELIX MOTIF and bind INTERFERON-inducible promoters to
control
GENE expression
. IRF
proteins
bind specific DNA sequences such as interferon-stimulated
response elements
,
interferon
regulatory
elements
, and the
interferon
consensus sequence.
History Note
English
:
2006
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50774
Unique Identifier:
D050835
Occurrence in VHL
:
Similar:
DeCS